A critical appraisal of controlled studies investigating malformation risks following pregabalin use in early pregnancy

Author:

Richardson Jonathan L.12ORCID,Damkier Per34ORCID,Diav‐Citrin Orna56,George Nathan1,Greenall Amanda J.1,Oliver Alison M.1,Stephens Sally12,Hodson Kenneth K.17

Affiliation:

1. UK Teratology Information Service Newcastle upon Tyne Hospitals NHS Foundation Trust Newcastle upon Tyne UK

2. Institute of Health and Society Newcastle University Newcastle upon Tyne UK

3. Department of Clinical Pharmacology Odense University Hospital Odense Denmark

4. Department of Clinical Research University of Southern Denmark Odense Denmark

5. The Israeli Teratology Information Service, Ministry of Health Jerusalem Israel

6. The Hebrew University Hadassah Medical School Jerusalem Israel

7. Women's Services Newcastle Upon Tyne NHS Foundation Trust, Royal Victoria Infirmary Newcastle upon Tyne UK

Funder

Christie NHS Foundation Trust

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Reference31 articles.

1. Pregabalin: Its Pharmacology and Use in Pain Management

2. Upjohn UK Limited.Summary of product characteristics: Lyrica 100 mg hard capsules.2022August 2022.www.medicines.org.uk/emc/product/10303/smpc

3. US Food and Drug Adminstration (FDA).Pharmacology review Lyrica® Pregabalin capsules.2004August 2022.www.accessdata.fda.gov/drugsatfda_docs/label/2006/021446s002 s003lbl.pdf

4. European Medicines Agency.Summary of the European public assessment report: Lyrica pregabalin.2022August 2022.www.ema.europa.eu/en/medicines/human/EPAR/lyrica

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