Empagliflozin reduces myocardial ketone utilization while preserving glucose utilization in diabetic hypertensive heart disease: A hyperpolarized 13 C magnetic resonance spectroscopy study
Author:
Affiliation:
1. Singapore Bioimaging Consortium, Agency for Science, Technology and Research; Singapore
2. National Heart Centre Singapore and Duke-National University of Singapore; Singapore
Funder
Asian neTwork for Translational Research and Cardiovascular Trials, ATTRaCT
A*STAR Biomedical Research Council
Publisher
Wiley
Subject
Endocrinology,Endocrinology, Diabetes and Metabolism,Internal Medicine
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/dom.13536/fullpdf
Reference32 articles.
1. Diabetes and cardiovascular risk factors: the Framingham study;Kannel;Circulation,1979
2. Evaluating the cardiovascular safety of new medications for type 2 diabetes: time to reassess?;Smith;Diabetes Care,2016
3. Empagliflozin, cardiovascular outcomes, and mortality in type 2 diabetes;Zinman;N Engl J Med,2015
4. Myocardial fatty acid metabolism in health and disease;Lopaschuk;Physiol Rev,2010
5. Regulation of sarcolemmal transport of substrates in the healthy and diseased heart;Glatz;Cardiovasc Drugs Ther,2006
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