1. Department of Cardiovascular Sciences, University of Leicester, Division of Anaesthesia, Critical Care and Pain Management; Leicester Royal Infirmary; Leicester LE2 7LX UK
2. Institute for Lung Health, Department of Infection, Immunity and Inflammation and Health Sciences; University of Leicester; Leicester UK
3. Department of Experimental Medicine, Section of Pharmacology L Donatelli,; Second University of Naples; Naples Italy
4. Department of Clinical and Experimental Medicine, Division of Immunology; Second University of Naples; Naples Italy
5. Department of Chemical and Pharmaceutical Sciences; University of Ferrara; Ferrara Italy
6. Department of Medical Sciences, Section of Pharmacology; University of Ferrara; Ferrara Italy