Somapacitan, a once-weekly reversible albumin-binding GH derivative, in children with GH deficiency: A randomized dose-escalation trial

Author:

Battelino Tadej1,Rasmussen Michael Højby2ORCID,De Schepper Jean3,Zuckerman-Levin Nehama4,Gucev Zoran5,Sävendahl Lars6,

Affiliation:

1. Faculty of Medicine; UMC-University Children's Hospital; University of Ljubljana; Ljubljana Slovenia

2. Global Development; Novo Nordisk A/S; Bagsvaerd Denmark

3. Division of Paediatric Endocrinology; UZ Brussel; Brussels Belgium

4. Pediatric and Obesity Clinic; Rambam Medical Center and Bruce Rappaport Faculty of Medicine; Haifa Israel

5. University Children's Hospital; Skopje Macedonia

6. Department of Women's and Children's Health; Karolinska Institutet; Pediatric Endocrinology Unit; Karolinska University Hospital; Stockholm Sweden

Funder

Novo Nordisk

Publisher

Wiley

Subject

Endocrinology, Diabetes and Metabolism,Endocrinology

Reference27 articles.

1. GH safety workshop position paper: a critical appraisal of recombinant human GH therapy in children and adults;Allen;Eur J Endocrinol,2016

2. Patient outcomes in the GHMonitor: the effect of delivery device on compliance and growth;Desrosiers;Pediat Endocrinol Rev,2005

3. Monitoring of concordance in growth hormone therapy;Kapoor;Arch Dis Child,2008

4. Compliance and persistence in pediatric and adult patients receiving growth hormone therapy;Rosenfeld;Endocr Pract,2008

5. Miller BS Crawford M McNamara A 2014 Reduced medication possession ratio is associated with lower response to growth hormone therapy

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