Significant use of non‐evidence‐based therapeutics in a cohort of Australian fibromyalgia patients

Author:

Warren Zachary1ORCID,Guymer Emma12,Mezhov Veronica12ORCID,Littlejohn Geoffrey12

Affiliation:

1. School of Clinical Sciences, Faculty of Medicine, Nursing and Health Sciences Monash University Melbourne Victoria Australia

2. Department of Rheumatology Monash Health Melbourne Victoria Australia

Abstract

AbstractBackgroundFibromyalgia is a common condition characterised by chronic widespread musculoskeletal pain and central sensitivity features. Appropriate management requires a multidisciplinary approach prioritising non‐pharmacological strategies. Evidence‐based fibromyalgia medications are not always easily available, effective or tolerated.AimTo characterise actual medication usage in Australian fibromyalgia patients.MethodsDemographic and clinical data, including medication use information, were gathered by chart review from patients attending the Monash Fibromyalgia Clinic between January 2019 and June 2022. Eligible patients were invited to complete an anonymous questionnaire between June and August 2022 to assess current therapeutic use. The questionnaire assessed fibromyalgia clinical features by using the Revised Fibromyalgia Impact Questionnaire and the 2016 modified American College of Rheumatology Fibromyalgia criteria.ResultsThe chart review included 474 patients, and 108 participants completed the questionnaire. Most chart review (78.7%) and questionnaire participants (85.2%) reported using at least one medication for their fibromyalgia. 48.5% of chart review patients and 58.3% of questionnaire participants reported using at least one evidence‐based medication, usually amitriptyline, duloxetine or pregabalin. However, the most common individual medications for questionnaire participants were non‐steroidal anti‐inflammatory drugs (48.2%), paracetamol (59.3%) and opioids (34.3%), with most opioids being typical opioids. Among questionnaire participants, 14.8% reported using cannabinoids, and 70.4% reported using at least one supplement, vitamin or herbal/naturopathic preparation. Not all medication or substance use was recorded during clinic appointments.ConclusionFibromyalgia patients engage in various pharmacotherapeutic strategies that are not always evidence‐based or disclosed to their treating clinicians.

Publisher

Wiley

Subject

Internal Medicine

Reference39 articles.

1. The relation of physical comorbidity and multimorbidity to fibromyalgia, widespread pain, and fibromyalgia‐related variables;Wolfe F;J Rheumatol,2020

2. The science of fibromyalgia;Clauw DJ;Mayo Clin Proc,2011

3. Neurogenic inflammation in fibromyalgia;Littlejohn G;Semin Immunopathol,2018

4. Central processes underlying fibromyalgia;Littlejohn G;Eur Med J,2018

5. The hypothalamo–pituitary–adrenal axis in chronic fatigue syndrome and fibromyalgia syndrome;Tanriverdi F;Stress,2007

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3