Pharmaceutical management of acute radiation dermatitis in the German speaking radiation oncology community

Author:

Layer Julian P.12ORCID,Layer Katharina1,Glasmacher Andrea R.1,Sarria Gustavo R.1,Böhner Alexander M. C.1,Layer Yonah L.1,Dejonckheere Cas S.1,Wiegreffe Shari1,Nour Youness1,Caglayan Lara1,Grau Franziska1,Feyer Petra3,Baumert Brigitta G.4,Baumann René5,Krug David6,Scafa Davide1,Leitzen Christina1,Landsberg Jennifer7,Giordano Frank A.89,Schmeel Leonard Christopher1,

Affiliation:

1. Department of Radiation Oncology University Hospital Bonn University of Bonn Bonn Germany

2. Institute of Experimental Oncology University Hospital Bonn University of Bonn Bonn Germany

3. Department of Radiation Oncology Vivantes Hospital Neukölln Berlin Germany

4. Institute of Radiation Oncology Cantonal Hospital Graubünden Chur Switzerland

5. Department of Radiation Oncology St. Marien Hospital Siegen Siegen Germany

6. Department of Radiation Oncology University Medical Center Schleswig‐Holstein Kiel Germany

7. Department of Dermatology University Hospital Bonn University of Bonn Bonn Germany

8. Department of Radiation Oncology University Hospital Mannheim University of Heidelberg Mannheim Germany

9. DKFZ Hector Cancer Institute University Medical Center Mannheim Mannheim Germany

Abstract

SummaryBackgroundRadiation dermatitis (RD) remains the most common side effect in radiation therapy (RT) with various pharmaceutical options available for prevention and treatment. We sought to determine pharmaceutical management patterns of radiation dermatitis among radiation oncology professionals.MethodsWe conducted a survey on RD among the German‐speaking community of radiation oncologists inquiring for their opinion on preventive and therapeutic pharmaceutical approaches for acute RD.Results244 health professionals participated. Dexpanthenol lotion is the agent most widely used both for prevention (53.0%) and treatment (76.9%) of RD, followed by urea (29.8%) for prevention and corticosteroids (46.9%) for treatment. A wide range of substances is used by participants, though the overall experience with them is rather limited. 32.5% of participants do generally not recommend any preventative treatment. 53.4% of participants recommend alternative medicine for RD management. While seldomly used, corticosteroids were considered most effective in RD therapy, followed by dexpanthenol and low‐level laser therapy. A majority of participants prefers moist over dry treatment of moist desquamation and 43.8% prescribe antiseptics.ConclusionsPharmaceutical management of RD in the German‐speaking radiation oncology community remains controversial, inconsistent, and partially not supported by evidence‐based medicine. Stronger evidence level and interdisciplinary consensus is required amongst practitioners to improve these care patterns.

Publisher

Wiley

Subject

Dermatology

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