A pig-to-mouse coronary artery transplantation model for investigating the pathogenicity of anti-pig antibody

Author:

Lin Yi12,Miyagi Naoto1,Byrne Guerard W.13,Du Zeji1,Kogelberg Heide3,Gazi Mozammel H.1,Tazelaar Henry D.4,Wang Chunsheng2,McGregor Christopher G. A.13

Affiliation:

1. Department of Surgery; Mayo Clinic; Rochester MN USA

2. Department of Cardiovascular Surgery; Zhongshan Hospital of Fudan University; Shanghai China

3. Institute of Cardiovascular Science; University College London; London UK

4. Department of Laboratory Medicine and Pathology; Mayo Clinic; Scottsdale AZ USA

Funder

National Institute of Allergy and Infectious Diseases

Comprehensive Biomedical Research Centre

Institut national de la santé et de la recherche médicale

National Institute for Health Research University College London Hospitals Biomedical Research Centre

Publisher

Wiley

Subject

Transplantation,Immunology

Reference41 articles.

1. Cardiac xenotransplantation: progress and challenges;Byrne;Curr Opin Organ Transplant,2012

2. Identification of carbohydrate structures that bind human antiporcine antibodies: Implications for discordant xenografting in humans;Good;Transplant Proc,1992

3. In vivo immunoadsorption of antipig antibodies in baboons using a specific gala1-3gal column;Taniguchi;Transplantation,1996

4. Depletion of anti-Gala1-3Gal antibody in baboons by specific a-Gal immunoaffinity columns;Kozlowski;Xenotransplantation,1998

5. Plasma perfusion by apheresis through a Gal immunoaffinity column successfully depletes anti-Gal antibody: experience with 320 aphereses in baboons;Watts;Xenotransplantation,2000

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