Inclusion of homologous DNA in nuclease‐mediated gene targeting facilitates a higher incidence of bi‐allelically modified cells

Author:

Beaton Benjamin P.1,Kwon Deug‐Nam2,Choi Yun‐Jung2,Kim Jae‐Hwan3,Samuel Melissa S.1,Benne Joshua A.1,Wells Kevin D.1,Lee Kiho4,Kim Jin‐Hoi2,Prather Randall S.1

Affiliation:

1. Division of Animal Sciences University of Missouri Columbia MO USA

2. Department of Animal Biotechnology Konkuk University Seoul Korea

3. CHA Stem Cell Institute Graduate School of Life Science and Biotechnology Pochon CHA University Seoul Korea

4. Department of Animal and Poultry Sciences Virginia Tech Blacksburg VA USA

Publisher

Wiley

Subject

Transplantation,Immunology

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1. Histotripsy Ablation in Preclinical Animal Models of Cancer and Spontaneous Tumors in Veterinary Patients: A Review;IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control;2022-01

2. Current progress of genome editing in livestock;Theriogenology;2020-07

3. The Possible Role of Anti-Neu5Gc as an Obstacle in Xenotransplantation;Frontiers in Immunology;2020-04-15

4. Sialic acid and xenotransplantation;Sialic Acids and Sialoglycoconjugates in the Biology of Life, Health and Disease;2020

5. Use of gene-editing technology to introduce targeted modifications in pigs;Journal of Animal Science and Biotechnology;2018-01-29

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