A model‐based approach to investigating the relationship between glucose‐insulin dynamics and dapagliflozin treatment effect in patients with type 2 diabetes

Author:

Shah Millie1ORCID,Stolbov Leonid2ORCID,Yakovleva Tatiana2ORCID,Tang Weifeng1ORCID,Sokolov Victor2ORCID,Penland Robert C.3ORCID,Boulton David1ORCID,Parkinson Joanna4ORCID

Affiliation:

1. Clinical Pharmacology and Quantitative Pharmacology Clinical Pharmacology and Safety Sciences, R&D, AstraZeneca Gaithersburg Maryland

2. M&S Decisions Moscow Russia

3. Clinical Pharmacology and Quantitative Pharmacology Clinical Pharmacology and Safety Sciences, R&D, AstraZeneca Waltham Massachusetts

4. Clinical Pharmacology and Quantitative Pharmacology Clinical Pharmacology and Safety Sciences, R&D, AstraZeneca Gothenburg Sweden

Publisher

Wiley

Subject

Endocrinology,Endocrinology, Diabetes and Metabolism,Internal Medicine

Cited by 5 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. A mechanistic modeling platform of SGLT2 inhibition: Implications for type 1 diabetes;CPT: Pharmacometrics & Systems Pharmacology;2023-03-16

2. Algorithms and methodological challenges in the development and application of quantitative systems pharmacology models: a case study in type 2 diabetes;Russian Journal of Numerical Analysis and Mathematical Modelling;2022-11-01

3. Analysis of pharmacological data using mathematical modeling approach;Proceedings of the International Conference "Mathematical Biology and Bioinformatics";2022-10-27

4. Recent applications of quantitative systems pharmacology and machine learning models across diseases;Journal of Pharmacokinetics and Pharmacodynamics;2021-10-20

5. Dapagliflozin Mediates Plin5/PPARα Signaling Axis to Attenuate Cardiac Hypertrophy;Frontiers in Pharmacology;2021-09-23

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