Brca2 abrogation engages with the alternative lengthening of telomeres via break‐induced replication
Author:
Affiliation:
1. Department of Biological Sciences Institute of Molecular Biology and Genetics (IMBG) Seoul National University South Korea
2. Department of Biomedical Engineering UNIST Ulsan Korea
3. Clinomics Inc. Ulsan Korea
Funder
Samsung Science and Technology Foundation
Publisher
Wiley
Subject
Cell Biology,Molecular Biology,Biochemistry
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1111/febs.14796
Reference55 articles.
1. Alternative lengthening of telomeres: models, mechanisms and implications
2. Two Survivor Pathways That Allow Growth in the Absence of Telomerase Are Generated by Distinct Telomere Recombination Events
3. Interchromosomal Homology Searches Drive Directional ALT Telomere Movement and Synapsis
4. Break-induced telomere synthesis underlies alternative telomere maintenance
5. Alternative lengthening of human telomeres is a conservative DNA replication process with features of break‐induced replication
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1. Disruption of G-quadruplex dynamicity by BRCA2 abrogation instigates phase separation and break-induced replication at telomeres;Nucleic Acids Research;2024-04-08
2. Inhibition of p53 and ATRX increases telomeric recombination in primary fibroblasts;FEBS Open Bio;2023-08-03
3. Targeting the BRCA1/2 deficient cancer with PARP inhibitors: Clinical outcomes and mechanistic insights;Frontiers in Cell and Developmental Biology;2023-03-22
4. Telomere Fragility and MiDAS: Managing the Gaps at the End of the Road;Genes;2023-01-29
5. Dynamic interaction of BRCA2 with telomeric G-quadruplexes underlies telomere replication homeostasis;Nature Communications;2022-06-13
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