A case of lung adenocarcinoma with a novel CD74 ‐ ROS1 fusion variant identified by comprehensive genomic profiling that responded to crizotinib and entrectinib

Author:

Hashiguchi Mizuha Haraguchi1ORCID,Sato Takashi123ORCID,Watanabe Rinako1,Kagyo Junko1,Matsuzaki Tomohiko4,Domoto Hideharu5,Kato Terufumi6,Nakahara Yoshiro26,Yokose Tomoyuki7,Hiroshima Yukihiko8,Shiomi Tetsuya1

Affiliation:

1. Division of Pulmonary Medicine, Department of Medicine Keiyu Hospital Yokohama Japan

2. Department of Respiratory Medicine Kitasato University School of Medicine Sagamihara Japan

3. Division of Pulmonary Medicine, Department of Medicine Keio University School of Medicine Tokyo Japan

4. Department of Surgery Keiyu Hospital Yokohama Japan

5. Department of Pathology Keiyu Hospital Yokohama Japan

6. Division of Pulmonary Medicine Kanagawa Cancer Center Yokohama Japan

7. Division of Pathology Kanagawa Cancer Center Yokohama Japan

8. Center for Cancer Genome Medicine Kanagawa Cancer Center Yokohama Japan

Publisher

Wiley

Subject

Pulmonary and Respiratory Medicine,Oncology,General Medicine

Reference20 articles.

1. ROS1 Rearrangements Define a Unique Molecular Class of Lung Cancers

2. A catalog of 5′ fusion partners in ROS1‐positive NSCLC circa 2020;Ou SI;JTO Clin Res Rep,2020

3. Beyond ALK‐RET, ROS1 and other oncogene fusions in lung cancer;Kohno T;Transl Lung Cancer Res,2015

4. Crizotinib in ROS1-Rearranged Non–Small-Cell Lung Cancer

5. Open-Label, Multicenter, Phase II Study of Ceritinib in Patients With Non–Small-Cell Lung Cancer Harboring ROS1 Rearrangement

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