Heterogeneous responses and resistant mechanisms to crizotinib in ALK -positive advanced non-small cell lung cancer

Author:

Kang Jin12,Chen Hua-Jun2,Zhang Xu-Chao2,Su Jian2,Zhou Qing2ORCID,Tu Hai-Yan2,Wang Zhen2,Wang Bin-Chao2,Zhong Wen-Zhao2,Yang Xue-Ning2,Chen Zhi-Hong2,Ding Yan3,Wu Xue3,Wang Mei4,Fu Jian-Gang4,Yang Zhenfan4,Zhang Xian5,Shao Yang W.36,Wu Yi-Long27,Yang Jin-Ji12ORCID

Affiliation:

1. Guangdong Cardiovascular Institute; Guangdong General Hospital and Guangdong Academy of Medical Sciences; Guangzhou China

2. Division of Pulmonary Oncology, Guangdong Lung Cancer Institute; Guangdong General Hospital and Guangdong Academy of Medical Sciences; Guangzhou China

3. Translational Medicine Research Institute; Geneseeq Technology Inc.; Toronto, Ontario Canada

4. BioScience Department; Dizal (Jiangsu) Pharmaceutical Co. Ltd; Shanghai China

5. Medical Department; Nanjing Geneseeq Technology Inc.; Nanjing China

6. School of Public Health; Nanjing Medical University; Nanjing China

7. Medical Research Center; Guangdong General Hospital and Guangdong Academy of Medical Sciences; Guangzhou China

Funder

Guangdong Provincial Key Laboratory of Lung Cancer Translational Medicine

National Key Technology R&D Program of the Ministry of Science and Technology of China

Special Fund of Public Interest by National Health and Family Control Committee

National Key R&D Program of China

the Project of the National Natural Science Funding of China

Publisher

Wiley

Subject

Pulmonary and Respiratory Medicine,Oncology,General Medicine

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