Affiliation:
1. University of Michigan Health Sparrow Hospital‐Michigan State University Lansing Michigan USA
Abstract
AbstractIntroductionLung and bronchus cancer is a leading cause of death in the United States. Compared with the national average, Michigan has an increased mortality rate and low early screening and treatment rates. This study aimed to explore the epidemiological trends and assess overall survival (OS) of patients diagnosed with lung cancer in Michigan from 1996 to 2017.MethodsData was acquired from the Michigan Cancer Surveillance Program (MCSP). Log‐rank test was used to test OS among the time periods, univariate and multivariate cox regression models were employed to determine factors that significantly affected OS. We hypothesized that the introduction of more inclusive lung cancer screening guidelines in 2013 would improve OS for patients diagnosed after its implementation and that individual characteristics and tumor characteristics would both affect OS.ResultsNotably, 153 742 individuals met inclusion criteria: 54.22% male and 45.78% female. Mean age at diagnosis was 69 years. No significant difference in OS was found among the three time periods (p = 0.99). Univariate analyses identified four individual characteristics associated with reduced OS: age at diagnosis, male sex, American Indian race, and living in rural or urban area. Reduced OS was associated with primary sites tumors at main bronchus, lung base, or within overlapping lobes, and SEER stage 7.ConclusionsThis study highlights several factors that influence OS. Consideration of these factors may be helpful as a community outreach tool to help increase early detection and reduce overall mortality.
Reference11 articles.
1. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries
2. Lung Cancer Screening
3. Invasive Lung Cancer Incidence by Age at Diagnosis Michigan Residents 1985–2020. Invasive Cancer Incidence by Age at Diagnosis. [cited 2024 Mar 17]. Available from:vitalstats.michigan.gov/osr/cancer/candiag.ASP?DxId=IncAgeDiagLung&CoType=0&CoCode=0&AgeID=1