Lending a helping hand, screening chemical libraries for compounds that enhance β-hexosaminidase A activity in GM2 gangliosidosis cells
Author:
Publisher
Wiley
Subject
Cell Biology,Molecular Biology,Biochemistry
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/j.1742-4658.2007.06040.x/fullpdf
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4. Crystallographic structure of human beta-hexosaminidase A: interpretation of Tay-Sachs mutations and loss of G(M2) ganglioside hydrolysis;Lemieux;J Mol Biol,2006
5. The GM2 activator protein, its roles as a co-factor in GM2 hydrolysis and as a general glycolipid transport protein;Mahuran;Biochim Biophys Acta,1998
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