Tutorial on Monoclonal Antibody Pharmacokinetics and Its Considerations in Early Development

Author:

Ovacik Meric1,Lin Kedan2

Affiliation:

1. Department of Preclinical and Translational Pharmacokinetics; Genentech, Inc.; South San Francisco California USA

2. Clinical Pharmacology; NGM Biopharmaceuticals, Inc.; South San Francisco California USA

Publisher

Wiley

Subject

General Pharmacology, Toxicology and Pharmaceutics,General Biochemistry, Genetics and Molecular Biology,General Medicine,General Neuroscience

Reference100 articles.

1. Antibodies to watch in 2017;Reichert;MAbs.,2017

2. Building better monoclonal antibody-based therapeutics;Weiner;Nat. Rev. Cancer.,2015

3. FDA Purple Book: Lists of Licensed Biological Products with Reference Product Exclusivity and Biosimilarity or Interchangeability Evaluations 2016 https://www.fda.gov/Drugs/DevelopmentApprovalProcess/HowDrugsareDevelopedandApproved/ApprovalApplications/TherapeuticBiologicApplications/Biosimilars/ucm411418.htm

4. Atlas of Immunology

5. Continuous cultures of fused cells secreting antibody of predefined specificity;Kohler;Nature,1975

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