Acute myeloid leukaemia (AML) with t(6;9)(p23;q34) is associated with poor outcome in childhood AML regardless ofFLT3-ITD status: a report from the Children's Oncology Group

Author:

Tarlock Katherine12,Alonzo Todd A.34,Moraleda Pilar P.5,Gerbing Robert B.34,Raimondi Susana C.46,Hirsch Betsy A.47,Ravindranath Yaddanapudi48,Lange Beverly49,Woods William G.410,Gamis Alan S.411,Meshinchi Soheil124

Affiliation:

1. Clinical Research Division; Fred Hutchinson Cancer Research Center; Seattle WA USA

2. Department of Pediatrics; University of Washington School of Medicine; Seattle WA USA

3. Keck School of Medicine; University of Southern California; Arcadia CA USA

4. Children's Oncology Group; Arcadia CA USA

5. Hematology and Blood and Marrow Transplant Program; Hospital Universitario Central de Asturias; Oviedo Spain

6. Department of Pathology; St. Jude Children's Research Hospital; Memphis TN USA

7. Department of Laboratory Medicine and Pathology; University of Minnesota Medical Center; Minneapolis MN USA

8. Carman and Ann Adams Department of Pediatrics; Division of Hematology/Oncology; Children's Hospital of Michigan; Detroit MI USA

9. Children's Hopital of Philadelphia; Philadelphia PA USA

10. Aflac Cancer Center and Blood Disorders Service; Children's Healthcare of Atlanta; Atlanta GA USA

11. Children's Mercy Hospitals and Clinics; Kansas City MO USA

Funder

National Institutes of Health

Publisher

Wiley

Subject

Hematology

Reference15 articles.

1. Improved outcome after stem-cell transplantation in FLT3/ITD-positive AML;Bornhäuser;Blood,2007

2. AAML03P1, a pilot study of the safety of gemtuzumab ozogamicin in combination with chemotherapy for newly diagnosed childhood acute myeloid leukemia: a report from the Children's Oncology Group;Cooper;Cancer,2012

3. Remission rates in childhood acute myeloid leukemia (AML) utilizing a dose-intensive induction regimen with or without gemtuzumab ozogamicin (GO): initial results from the Children's Oncology Group phase III trial, AAML0531;Gamis;Blood (ASH Annual Meeting Abstracts),2010

4. Cytogenetics of childhood acute myeloid leukemia: United Kingdom Medical Research Council Treatment Trials AML10 and 12;Harrison;Journal of Clinical Oncology,2010

5. Prognostic factors for acute myeloid leukemia patients with t(6;9)(p23;q34) who underwent an allogeneic hematopoietic stem cell transplant;Ishiyama;Leukemia,2012

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