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BRAF and NRAS Mutations Are Frequent in Nodular Melanoma but Are not Associated with Tumor Cell Proliferation or Patient Survival

  • Published:2005-08 Issue:2 Volume:125 Page:312-317
  • ISSN:0022-202X
  • Container-title:Journal of Investigative Dermatology
  • language:en
  • Short-container-title:Journal of Investigative Dermatology

Author:

Akslen Lars A.,Angelini Sabrina,Straume Oddbjørn,Bachmann Ingeborg M.,Molven Anders,Hemminki Kari,Kumar Rajiv

Publisher

Wiley

Subject

Cell Biology,Dermatology,Molecular Biology,Biochemistry

Reference26 articles.

1. Activation of B-raf in non-malignant nevi predicts a novel tumor suppressor gene in melanoma (MAP kinase phosphatase);Arbiser;J Invest Dermatol,2003

2. Thickness, cross-sectional areas and depth of invasion in the prognosis of cutaneous melanoma;Breslow;Ann Surg,1970

3. BRAF and RAS mutations in human lung cancer and melanoma;Brose;Cancer Res,2002

4. The histogenesis and biologic behavior of primary human malignant melanomas of the skin;Clark;Cancer Res,1969

5. Exon 15 BRAF mutations are uncommon in melanomas arising in nonsun-exposed sites;Cohen;Clin Cancer Res,2004
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