Effect of pregnancy on emtricitabine pharmacokinetics

Author:

Stek AM1,Best BM,Luo W2,Capparelli E,Burchett S3,Hu C4,Li H4,Read JS5,Jennings A6,Barr E7,Smith E8,Rossi SS9,Mirochnick M10

Affiliation:

1. Department of Obstetrics and Gynecology; University of Southern California School of Medicine; Los Angeles; CA; USA

2. Skaggs School of Pharmacy and Pharmaceutical Sciences; University of California San Diego; La Jolla; CA; USA

3. Children's Hospital; Boston; MA; USA

4. Statistical and Data Analysis Center; Harvard School of Public Health; Boston; MA; USA

5. Pediatric, Adolescent, and Maternal AIDS Branch; Eunice Kennedy Shriver National Institute of Child Health and Human Development; Bethesda; MD; USA

6. Frontier Science and Technology Research Foundation; Amherst; NY; USA

7. The Children's Hospital; Aurora; CO; USA

8. National Institute of Allergy and Infectious Diseases; Bethesda; MD; USA

9. Department of Pediatrics; University of California San Diego, Rady Children's Hospital San Diego; San Diego; CA; USA

10. Boston University School of Medicine; Boston; MA; USA

Publisher

Wiley

Subject

Pharmacology (medical),Infectious Diseases,Health Policy

Reference26 articles.

1. Panel on Treatment of HIV-Infected Pregnant Women and Prevention of Perinatal Transmission Recommendations for Use of Antiretroviral Drugs in Pregnant HIV-1-Infected Women for Maternal Health and Interventions to Reduce Perinatal HIV Transmission in the United States 2010 1 117 http://aidsinfo.nih.gov/ContentFiles/PerinatalGL.pdf

2. Antiretroviral pharmacology: special issues regarding pregnant women and neonates;Mirochnick;Clin Perinatol,2010

3. Drug transfer across the placenta. Considerations in treatment and research;Simone;Clin Perinatal,1994

4. Placental transfer of drugs administered to the mother;Pacifici;Clin Pharmacokinet,1995

5. U.S. Department of Health and Human Services, Food and Drug Administration, Center for Drug Evaluation and Research Draft guidance for industry: pharmacokinetics in pregnancy-study design, data analysis, and impact on dosing and labeling 2004 www.fda.gov/downloads/Drugs/GuidanceComplianceRegulatoryInformation/Guidances/UCM072133.pdf

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