Neuropeptide Y in the noradrenergic neurones induces obesity and inhibits sympathetic tone in mice

Author:

Vähätalo L. H.123,Ruohonen S. T.13,Mäkelä S.13,Kovalainen M.45,Huotari A.45,Mäkelä K. A.5,Määttä J. A.36,Miinalainen I.7,Gilsbach R.8,Hein L.8,Ailanen L.123,Mattila M.123,Eerola K.13,Röyttä M.9,Ruohonen S.110,Herzig K. -H.511,Savontaus E.1312

Affiliation:

1. Department of Pharmacology, Drug Development and Therapeutics; University of Turku; Turku Finland

2. Drug Research Doctoral Program; University of Turku; Turku Finland

3. Turku Center for Disease Modeling; University of Turku; Turku Finland

4. Faculty of Health Sciences; School of Pharmacy; Pharmaceutical Technology; University of Eastern Finland; Kuopio Finland

5. Institute of Biomedicine and Biocenter of Oulu; University of Oulu; Oulu Finland

6. Department of Cell Biology and Anatomy; Institute of Biomedicine; University of Turku; Turku Finland

7. Biocenter Oulu Electron Microscopy Core Facility; University of Oulu; Oulu Finland

8. Institute of Experimental and Clinical Pharmacology and Toxicology and BIOSS Centre for Biological Signalling Studies; University of Freiburg; Freiburg Germany

9. Department of Pathology; University of Turku; Turku Finland

10. Research Centre of Applied and Preventive Cardiovascular Medicine; University of Turku; Turku Finland

11. Medical Research Center Oulu and Oulu University Hospital; Oulu Finland

12. Unit of Clinical Pharmacology; Turku University Hospital; Turku Finland

Funder

Academy of Finland

European Foundation for the Study of Diabetes

Finnish Cultural Foundation

Publisher

Wiley

Subject

Physiology

Reference60 articles.

1. Metabolic alterations associated with the antidiabetic effect of beta 3-adrenergic receptor agonists in obese mice;Arbeeny;Am J Physiol,1995

2. Neuropeptide Y knockout mice reveal a central role of NPY in the coordination of bone mass to body weight;Baldock;PLoS ONE,2009

3. The protamine family of sperm nuclear proteins;Balhorn;Genome Biol,2007

4. Effect of diet on fat cell size and hormone-sensitive lipase activity;Berger;J Appl Physiol (1985),1999

5. Effects of intracerebroventricular injection of neuropeptide Y on energy metabolism;Billington;Am J Physiol,1991

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