The potentiating effect of hTFPI in the presence of hCD47 reduces the cytotoxicity of human macrophages
Author:
Affiliation:
1. Department of Bioscience and Biotechnology; Konkuk University; Seoul Korea
2. Korea Institute of Toxicology; Jeongeup-si Jeollabuk-do Korea
Funder
Cooperative Research Program for Agriculture Science & Technology Development
Publisher
Wiley
Subject
Transplantation,Immunology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/xen.12301/fullpdf
Reference22 articles.
1. Xenotransplantation - the future of corneal transplantation?;Hara;Cornea,2011
2. Overcoming the barriers to xenotransplantation: prospects for the future;Ekser;Expert Rev Clin Immunol,2010
3. Human CD47 expression permits survival of porcine cells in immunodeficient mice that express SIRPα capable of binding to human CD47;Wang;Cell Transplant,2011
4. Functional CD47/signal regulatory protein alpha (SIRP(alpha)) interaction is required for optimal human T- and natural killer- (NK) cell homeostasis in vivo;Legrand;Proc Natl Acad Sci USA,2011
5. Role for CD47-SIRPalpha signaling in xenograft rejection by macrophages;Ide;Proc Natl Acad Sci USA,2007
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2. Effects of human TFPI and CD47 expression and selectin and integrin inhibition during GalTKO.hCD46 pig lung perfusion with human blood;Xenotransplantation;2022-03
3. Pig‐to‐baboon lung xenotransplantation: Extended survival with targeted genetic modifications and pharmacologic treatments;American Journal of Transplantation;2021-09-20
4. Minimizing Ischemia Reperfusion Injury in Xenotransplantation;Frontiers in Immunology;2021-09-09
5. Human recombinant IL-10 reduces xenogenic cytotoxicity via macrophage M2 polarization;Biochemistry and Biophysics Reports;2020-12
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