A randomized phase 1b trial of the active site polymerase inhibitor nucleotide ATI ‐2173 in patients with chronic hepatitis B virus infection

Author:

Squires Katherine E.1ORCID,Ogilvie Lauren1,Jucov Alina23,Anastasiy Igor34,Ghicavii Nelli2,Huguet Jade5,Melara Rebeca5,Constantineau Martin5,De La Rosa Abel1,Mayers Douglas L.1

Affiliation:

1. Antios Therapeutics Doylestown Pennsylvania USA

2. ARENSIA Exploratory Medicine Republican Clinical Hospital Chisinau Moldova

3. Department of Infectious Diseases Nicolae Testemitanu State University of Medicine and Pharmacy Chisinau Moldova

4. ARENSIA Exploratory Medicine Kiev Ukraine

5. Altasciences, Montreal Quebec Canada

Publisher

Wiley

Subject

Virology,Infectious Diseases,Hepatology

Reference36 articles.

1. Hepatitis B Foundation.Hepatitis B facts and figures. Accessed October 20 2021.https://www.hepb.org/what‐is‐hepatitis‐b/what‐is‐hepb/facts‐and‐figures/

2. Chronic Hepatitis B Infection

3. EASL 2017 Clinical Practice Guidelines on the management of hepatitis B virus infection

4. Chronic hepatitis B virus infection

5. Targets and future direct-acting antiviral approaches to achieve hepatitis B virus cure

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