Mutant HrasG12V and KrasG12D have overlapping, but non-identical effects on hepatocyte growth and transformation frequency in transgenic mice

Author:

Figueiredo Marxa L.1,Stein Timothy J.1,Jochem Adam1,Sandgren Eric P.1

Affiliation:

1. Department of Pathobiological Sciences; School of Veterinary Medicine; University of Wisconsin-Madison; Madison; WI; USA

Publisher

Wiley

Subject

Hepatology

Reference32 articles.

1. A ras by any other name;Bar-Sagi;Mol Cell Biol,2001

2. Mutations in ras genes in experimental tumours of rodents;Sills;IARC Sci Publ,1999

3. Blocking oncogenic ras signaling for cancer therapy;Adjei;J Natl Cancer Inst,2001

4. Detection and identification of activated oncogenes in spontaneously occurring benign and malignant hepatocellular tumors of the B6C3F1 mouse;Reynolds;Proc Natl Acad Sci USA,1986

5. Activated oncogenes in B6C3F1 mouse liver tumors: implications for risk assessment;Reynolds;Science,1987

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