Striated duct adenoma: The cytological description of a rare entity

Author:

De La Torre Serrano Montserrat12ORCID,Alarcón García Lorenzo12ORCID,Colino Gallardo Ana María12,Vega‐Gonzalez Jesus12ORCID,Bergillos Giménez María Reyes12,Hernandez Martinez Desiré12,Garcia Egido Alejandro12,Iglesias Moreno María Cruz12,Pérez‐Alonso Pablo12,Plaza Hernandez José Carlos12,Fernández‐Aceñero M. Jesús12

Affiliation:

1. Department of Surgical Pathology, Health Research Institute “San Carlos” (IdISCC), Hospital Universitario Clínico San Carlos Universidad Complutense de Madrid Madrid Spain

2. Department of Otorhinolaryngology, Health Research Institute “San Carlos” (IdISCC), Hospital Universitario Clínico San Carlos Universidad Complutense de Madrid Madrid Spain

Abstract

AbstractIntroductionStriated duct adenoma is a benign salivary gland tumour recently recognized by the World Health Organization. To date, no report has described the cytological features of this entity.Materials and MethodsWe report the case of a 60‐year‐old woman with a tumour in the right parotid gland with a diameter greater than 2.4 cm confirmed by imaging tests.ResultsTwo fine‐needle aspiration cytologies (FNAC) were performed with inconclusive results, reporting epithelioid and spindle‐shaped cellularity, with little stroma, and nuclei with abundant pseudoinclusions. Myoepithelioma and Schwannoma were proposed as differential diagnoses. An immunocytochemical panel was performed, showing positivity for S‐100, SOX10, CK7 and vimentin, and negativity for both myoepithelial (p63 and calponin) and thyroid markers. In the absence of a conclusive diagnosis, the patient accepted surgery. The biopsy results confirmed diagnosis of striated duct adenoma, with immunohistochemical features superimposable to cytology.ConclusionLittle information is available in the literature, both on biopsy and, more strikingly, on cytology of this neoplasm. The aim of this work is to provide cytological characteristics that allow diagnosis of this entity with FNAC and thus avoid unnecessary surgeries.

Publisher

Wiley

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