High-affinity von Willebrand factor binding does not affect the anatomical or hepatocellular distribution of factor VIII in rats
Author:
Affiliation:
1. Vascular Biology Research Group; Department of Medical Biology; Faculty of Health Sciences; UiT The Arctic University of Norway; Tromsø Norway
2. Novo Nordisk A/S; Novo Nordisk Park; Måløv Denmark
Funder
Novo Nordisk
Publisher
Wiley
Subject
Hematology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/jth.13406/fullpdf
Reference51 articles.
1. Biological regulation of factor VIII activity;Kaufman;Annu Rev Med,1992
2. Modern haemophilia care;Berntorp;Lancet,2012
3. Human liver sinusoidal endothelial cells but not hepatocytes contain factor VIII;Shahani;J Thromb Haemost,2014
4. Secretion of coagulant factor VIII activity and antigen by in vitro cultivated rat liver sinusoidal endothelial cells;Hellman;Br J Haematol,1989
5. A conditional knockout mouse model reveals endothelial cells as the principal and possibly exclusive source of plasma factor VIII;Fahs;Blood,2014
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