Model to predict on‐treatment restoration of functional <scp>HBV</scp> ‐specific <scp>CD8</scp> <sup>+</sup> cell response foresees off‐treatment <scp>HBV</scp> control in <scp>eAg</scp> ‐negative chronic hepatitis B-Reference-Cited by-同舟云学术

Model to predict on‐treatment restoration of functional HBV ‐specific CD8 ⁺ cell response foresees off‐treatment HBV control in eAg ‐negative chronic hepatitis B

Published:2022-02-27 Issue:12 Volume:55 Page:1545-1559
ISSN:0269-2813
Container-title:Alimentary Pharmacology & Therapeutics
language:en
Short-container-title:Aliment Pharmacol Ther

Author:

Peña‐Asensio Julia¹,Calvo Henar²,Miquel Joaquín²,Sanz‐de‐Villalobos Eduardo²,González‐Praetorius Alejandro³,Torralba Miguel⁴⁵,Larrubia Juan‐Ramón²⁵^ORCID

Affiliation:

1. Department of Biology of Systems University of Alcalá Alcalá de Henares Spain

2. Section of Gastroenterology Guadalajara University Hospital Guadalajara Spain

3. Section of Microbiology Guadalajara University Hospital Guadalajara Spain

4. Service of Internal Medicine Guadalajara University Hospital Guadalajara Spain

5. Department of Medicine & Medical Specialties University of Alcalá Alcalá de Henares Spain

Funder

Instituto de Salud Carlos III

Publisher

Wiley

Subject

Pharmacology (medical),Gastroenterology,Hepatology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/apt.16850

Reference37 articles.

1. Direct ex vivo analysis of hepatitis B virus-specific CD8+ T cells associated with the control of infection

2. Characterization of Hepatitis B Virus (HBV)-Specific T-Cell Dysfunction in Chronic HBV Infection

3. Longitudinal Analysis of CD8 + T Cells Specific for Structural and Nonstructural Hepatitis B Virus Proteins in Patients with Chronic Hepatitis B: Implications for Immunotherapy

4. Viral Persistence Alters CD8 T-Cell Immunodominance and Tissue Distribution and Results in Distinct Stages of Functional Impairment

5. Effects of Hepatitis B Surface Antigen on Virus-Specific and Global T Cells in Patients With Chronic Hepatitis B Virus infection

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