JLK1486, aN,N-[(8-hydroxyquinoline)methyl]-substituted benzylamine analogue, inhibits melanoma proliferation and induces autophagy
Author:
Affiliation:
1. Department of Biochemistry and Microbiology; Nelson Mandela Metropolitan University; Port Elizabeth 6031 South Africa
2. Laboratoire de Chimie Biomoléculaire; CNRS-UMR 7288 IBDML; Marseille 13288 France
Funder
National Research Foundation of South Africa
Publisher
Wiley
Subject
Cell Biology,General Medicine
Reference16 articles.
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3. Discovery of a new family of bis-8-hydroxyquinoline substituted benzylamines with pro-apoptotic activity in cancer cells: synthesis, structure-activity relationship, and action mechanism studies;Moret;Eur. J. Med. Chem.,2009
4. Structure-activity relationships and mechanism of action of antitumor bis 8-hydroxyquinoline substituted benzylamines;Madonna;Eur. J. Med. Chem.,2010
5. Blood-brain barrier permeability and transport studies of JLK1486: a new antiglioblastoma drug;Barthelemy-Requin;Med. Chem. Res.,2012
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