<scp>MEK1</scp> ‐dependent <scp>MondoA</scp> phosphorylation regulates glucose uptake in response to ketone bodies in colorectal cancer cells-Reference-Cited by-同舟云学术

MEK1 ‐dependent MondoA phosphorylation regulates glucose uptake in response to ketone bodies in colorectal cancer cells

Published:2022-12-04 Issue:3 Volume:114 Page:961-975
ISSN:1347-9032
Container-title:Cancer Science
language:en
Short-container-title:Cancer Science

Author:

Zhu Yemin¹,Xu Nannan¹,Wu Siming²,Luan Yu²,Ke Huiyi²,Wu Lifang¹,Li Yakui¹,Lu Ying³,Xing Xindan⁴,Tian Na⁵,Liu Qi¹,Tong Lingfeng¹,Hu Lei¹,Ji Yingning¹,Chen Zhangbing¹,Zhang Ping¹,Tong Xuemei¹^ORCID

Affiliation:

1. Department of Biochemistry and Molecular Cell Biology Shanghai Key Laboratory for Tumor Microenvironment and Inflammation, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Shanghai Jiao Tong University School of Medicine Shanghai China

2. Department of Clinical Medicine Shanghai Jiao Tong University School of Medicine Shanghai China

3. Department of Biochemistry and Molecular Biology of School of Basic Medical Sciences Shanghai Medical College of Fudan University Shanghai China

4. Department of Ophthalmology Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine Shanghai China

5. Department of Neurology Shandong Provincial Hospital Affiliated to Shandong First Medical University Jinan Shandong China

Funder

National Key Research and Development Program of China

National Natural Science Foundation of China

Publisher

Wiley

Subject

Cancer Research,Oncology,General Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/cas.15667

Reference44 articles.

1. MondoA Is an Essential Glucose-Responsive Transcription Factor in Human Pancreatic β-Cells

2. MondoA coordinately regulates skeletal myocyte lipid homeostasis and insulin signaling

3. Extracellular Matrix Remodeling Regulates Glucose Metabolism through TXNIP Destabilization

4. AMPK-Dependent Degradation of TXNIP upon Energy Stress Leads to Enhanced Glucose Uptake via GLUT1

5. Glucose Controls Nuclear Accumulation, Promoter Binding, and Transcriptional Activity of the MondoA-Mlx Heterodimer