Androgen receptor (AR) splice variant 7 and full-length AR expression is associated with clinical outcome: a translational study in patients with castrate-resistant prostate cancer-Reference-Cited by-同舟云学术

Androgen receptor (AR) splice variant 7 and full-length AR expression is associated with clinical outcome: a translational study in patients with castrate-resistant prostate cancer

Published:2019-09-20 Issue:4 Volume:124 Page:693-700
ISSN:1464-4096
Container-title:BJU International
language:en
Short-container-title:BJU Int

Author:

Del Re Marzia¹,Crucitta Stefania¹,Sbrana Andrea²,Rofi Eleonora¹,Paolieri Federico²,Gianfilippo Giulia¹,Galli Luca²,Falcone Alfredo²,Morganti Riccardo³,Porta Camillo⁴⁵,Efstathiou Eleni⁶,van Schaik Ron⁷,Jenster Guido⁸,Danesi Romano¹^ORCID

Affiliation:

1. Unit of Clinical Pharmacology and Pharmacogenetics; Department of Clinical and Experimental Medicine; University of Pisa; Pisa Italy

2. Medical Oncology Unit; Department of Translational Research and New Technologies in Medicine; University of Pisa; Pisa Italy

3. Section of Statistics; Department of Clinical and Experimental Medicine; University of Pisa; Pisa Italy

4. Department of Internal Medicine; University of Pavia; Pavia Italy

5. Division of Translational Oncology; I.R.C.C.S. Istituti Clinici Scientifici Maugeri; Pavia Italy

6. Division of Cancer Medicine; Department of Genitourinary Medical Oncology; University of Texas MD Anderson Cancer Centre; Houston TX USA

7. Department of Clinical Chemistry; Erasmus University Medical Centre; Rotterdam The Netherlands

8. Department of Urology; Erasmus University Medical Centre; Rotterdam The Netherlands

Funder

Fondazione Cassa di Risparmio di Lucca

Sanofi Genzyme

Publisher

Wiley

Subject

Urology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/bju.14792/fullpdf

Reference22 articles.

1. Expression of androgen receptor splice variants in prostate cancer bone metastases is associated with castration-resistance and short survival;Hörnberg;PLoS One,2011

2. Pharmacogenetics of androgen signaling in prostate cancer: focus on castration resistance and predictive biomarkers of response to treatment;Del Re;Crit Rev Oncol Hematol,2018

3. Analytical validation and clinical qualification of a new immunohistochemical assay for androgen receptor splice variant-7 protein expression in metastatic castration-resistant prostate cancer;Welti;Eur Urol,2016

4. AR-V7 and resistance to enzalutamide and abiraterone in prostate cancer;Antonarakis;N Engl J Med,2014

5. The detection of androgen receptor splice variant 7 in plasma-derived exosomal RNA strongly predicts resistance to hormonal therapy in metastatic prostate cancer patients;Del Re;Eur Urol,2017

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