The histamine‐synthesizing enzyme histidine decarboxylase is upregulated by keratinocytes in atopic skin

Author:

Gutowska‐Owsiak D.1,Greenwald L.1,Watson C.1,Selvakumar T.A.1,Wang X.12,Ogg G.S.1

Affiliation:

1. MRC Human Immunology Unit NIHR Biomedical Research Centre University of Oxford John Radcliffe Hospital Weatherall Institute of Molecular Medicine Oxford OX3 9DS U.K

2. Department of Oral Medicine and Periodontology School of Stomatology the Fourth Military Medical University Xi'an China

Funder

Medical Research Council

Barrie Trust

British Skin Foundation

NIHR Biomedical Research Centre programme

Publisher

Wiley

Subject

Dermatology

Reference52 articles.

1. Histamine suppresses epidermal keratinocyte differentiation and impairs skin barrier function in a human skin model

2. Histamine exerts multiple effects on expression of genes associated with epidermal barrier function;Gutowska‐Owsiak D;J Invest Allergy Clin Immunol,2014

3. Basophil recruitment and activation in inflammatory skin diseases

4. Basophils, eosinophils, and mast cells in atopic and nonatopic asthma and in late-phase allergic reactions in the lung and skin

5. Histamine production in mouse epidermal keratinocytes is regulated during cellular differentiation;Fitzsimons C;Inflamm Res,2001

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