PDK1/Akt/PDE4D axis identified as a target for asthma remedy synergistic with β2AR agonists by a natural agent arctigenin

Author:

Fang R.123,Cui Q.1,Sun J.1,Duan X.1,Ma X.1,Wang W.1,Cheng B.1,Liu Y.1,Hou Y.12,Bai G.1

Affiliation:

1. State Key Laboratory of Medicinal Chemical Biology and College of Pharmacy; Tianjin Key Laboratory of Molecular Drug Research; Nankai University; Tianjin China

2. State Key Laboratory of Natural and Biomimetic Drugs; Peking University; Beijing China

3. State Key Laboratory of Medicinal Chemical Biology; Department of Biochemistry; College of Life Sciences; Nankai University; Tianjin China

Funder

National Natural Science Foundation of China

State Key Laboratory of Natural and Biomimetic Drugs

Specialized Research Fund for the Doctor Program of Higher Education of China

Key Program of the Natural Science Foundation of Tianjin, China

Publisher

Wiley

Subject

Immunology,Immunology and Allergy

Reference50 articles.

1. NHLBI National asthma education and prevention program Expert Panel Report 3: guidelines for the diagnosis and management of asthma NHLBI Full report 2007 2007 1 417

2. Pharma-cogenomics in asthma therapy: where are we and where do we go?;Park;Annu Rev Pharmacol Toxicol,2014

3. Biochemical basis of asthma therapy;Barnes;J Biol Chem,2011

4. Efficacy and side effects of beta 2-agonists by inhaled route in acute asthma in children: comparison of salbutamol, terbutaline, and fenoterol;Scalabrin;J Asthma,1996

5. Addition of intravenous beta(2)-agonists to inhaled beta(2)-agonists for acute asthma;Travers;Cochrane Database Syst Rev,2012

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3