TP53is not a prognostic marker—clinical consequences of a generally disregarded fact

Author:

Braunschmid Tamara1ORCID,Kührer Irene2,Mittlböck Martina3,Westerhoff Maria4,Kappel‐Latif Sonja5,Brammen Lindsay1,Krishnadath Kausilia K.6,Phillips Wayne A.7,Gnant Michael1,Kandioler Daniela1

Affiliation:

1. Department of SurgeryMedical University of Vienna Vienna Austria

2. Department of Internal Medicine IIIMedical University of Vienna Vienna Austria

3. Center for Medical StatisticsInformaticsand Intelligent SystemsMedical University of Vienna Vienna Austria

4. Department of PathologyUniversity of Michigan Ann Arbor Michigan

5. Department of SurgeryResearch LaboratoriesMedical University of Vienna Vienna Austria

6. Department of Translational GastroenterologyAcademic Medical CenterUniversity of Amsterdam Amsterdam the Netherlands

7. Peter MacCallum Cancer Centre Melbourne Victoria Australia

Publisher

Wiley

Subject

History and Philosophy of Science,General Biochemistry, Genetics and Molecular Biology,General Neuroscience

Reference36 articles.

1. Gene expression‐based prognostic and predictive markers for breast cancer: a primer for practicing pathologists;Kim C.;Arch. Pathol. Lab. Med.,2009

2. International Agency for Research on Cancer W.H.O. Somatic mutations. Accessed September 1 2017.http://p53.iarc.fr/TP53SomaticMutations.aspx.

3. p53 Mutations in Human Cancers

4. P53 abnormalities and outcomes in colorectal cancer: a systematic review

5. Prognostic Value of p53 Genetic Changes in Colorectal Cancer

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