Effects of a selective androgen receptor modulator (SARM), GSK2849466A, on stress urinary incontinence and bladder activity in rats with ovariectomy-induced oestrogen deficiency

Author:

Kadekawa Katsumi1,Kawamorita Naoki1,Shimizu Takahiro1,Kurobe Masahiro1,Turnbull Philip S.2,Chandra Sundeep2,Kambara Takahito3,Barton Joanna C.2,Russell Alan J.2,Yoshimura Naoki1ORCID

Affiliation:

1. Department of Urology; University of Pittsburgh; Pittsburgh PA USA

2. Muscle Metabolism DPU; GlaxoSmithKline; King of Prussia PA USA

3. Pathology, Translational Medicine & Comparative Pathobiology; GlaxoSmithKline; King of Prussia PA USA

Funder

National Institutes of Health

GlaxoSmithKline

Publisher

Wiley

Subject

Urology

Reference27 articles.

1. Recent advances in the neurophysiology of stress urinary incontinence;Chancellor;Scand J Urol Nephrol,2005

2. Urinary incontinence in US women: a population-based study;Melville;Arch Intern Med,2005

3. Prevalence of urinary incontinence and associated risk factors in postmenopausal women. Heart & Estrogen/Progestin Replacement Study (HERS) Research Group;Brown;Obstet Gynecol,1999

4. Parity, mode of delivery and pelvic floor disorders;Lucacs;Obstet Gynecol,2006

5. Effects of ovariectomy and estrogen replacement on the urethral continence reflex during sneezing in rats;Kitta;J Urol,2011

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