Melanocyte colonization and pigmentation of breast carcinoma: A case report

Author:

Khazaeli Mahyar1ORCID,Maruthi Vijaya Kadam1,See Sharlene2,Ondracek Theodore1,Gerami Pedram2

Affiliation:

1. Department of Pathology University at Buffalo Buffalo New York USA

2. Department of Dermatology, Section of Dermatopathology, Feinberg School of Medicine Northwestern University Chicago Illinois USA

Abstract

AbstractPigmented mammary Paget disease is a rare variant of mammary Paget disease that is often clinically misdiagnosed as a melanocytic lesion of the skin or nipple–areolar complex. Careful morphological assessment, along with the performance of adequate immunohistochemical stains, will help in achieving the right diagnosis and avoiding misdiagnosis of the entity as malignant melanoma. We report a rare case of pigmented mammary Paget disease with concomitant colonization of the underlying invasive ductal carcinoma by melanocytes mimicking melanoma.

Publisher

Wiley

Subject

Dermatology,Histology,Pathology and Forensic Medicine

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