Glucose-lowering with exogenous insulin monotherapy in type 2 diabetes: dose association with all-cause mortality, cardiovascular events and cancer

Author:

Holden S. E.1,Jenkins-Jones S.2,Morgan C. Ll.2,Schernthaner G.3,Currie C. J.1

Affiliation:

1. Cochrane Institute of Primary Care and Public Health; School of Medicine, Cardiff University, The Pharma Research Centre; Cardiff Medicentre, Cardiff UK

2. Global Epidemiology, Pharmatelligence, Cardiff Medicentre; Cardiff UK

3. Department of Medicine; Rudolfstiftung Hospital Vienna; Vienna Austria

Funder

Cardiff University

Abbott

ALK

Astellas

Diabetes UK

Engineering and Physical Sciences Research Council

EASD

Ferring

GSK

Jenson (Internis)

Lilly

Medical Research Council, Medtronic

MSD

National Health Service

Norgine

Pfizer

Sanofi-Aventis

Shire

Wyeth

Publisher

Wiley

Subject

Endocrinology,Endocrinology, Diabetes and Metabolism,Internal Medicine

Reference43 articles.

1. How many people inject insulin? UK estimates from 1991 to 2010;Holden;Diabetes Obes Metab,2014

2. Evaluation of the incremental cost to the National Health Service of prescribing analogue insulin;Holden;BMJ Open,2011

3. National Institute for Heath and Clinical Excellence Type 2 diabetes: the management of type 2 diabetes. NICE clinical guideline 87 2009 http://www.nice.org.uk/guidance/cg87

4. Survival as a function of HbA(1c) in people with type 2 diabetes: a retrospective cohort study;Currie;Lancet,2010

5. Glycemic control and risk of cardiovascular disease hospitalization and all-cause mortality;Nichols;J Am Coll Cardiol,2013

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