Roscovitine is a proteostasis regulator that corrects the trafficking defect of F508del-CFTR by a CDK-independent mechanism-Reference-Cited by-同舟云学术

Roscovitine is a proteostasis regulator that corrects the trafficking defect of F508del-CFTR by a CDK-independent mechanism

Author:

Norez C¹,Vandebrouck C¹,Bertrand J¹,Noel S¹,Durieu E²,Oumata N³,Galons H⁴,Antigny F⁵,Chatelier A¹,Bois P¹,Meijer L²³,Becq F¹

Affiliation:

1. Institut de Physiologie et Biologie Cellulaires; Université de Poitiers; Poitiers France

2. Protein Phosphorylation and Human Disease Group; Station Biologique; Roscoff France

3. ManRos Therapeutics; Centre de Perharidy; Roscoff France

4. Université Paris-Descartes; Laboratoire de Pharmacochimie; Paris France

5. Department of Cell Physiology and Metabolism; University of Geneva Medical School; Geneva Switzerland

Funder

French association ‘Vaincre la Mucoviscidose’

Swiss National Science Foundation

Carlos and Elsie de Reuter

Publisher

Wiley

Subject

Pharmacology

Link

Reference82 articles.

1. Seliciclib in malignancies;Aldoss;Expert Opin Investig Drugs,2009

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