Evidence of neural crest cell origin of a DICER1 mutant CNS sarcoma in a child with DICER1 syndrome and NRAS‐mutant neurocutaneous melanosis

Author:

Schweizer Leonille12ORCID,Hartmann Wolfgang3,Koch Arend12,Nunninger Maximilian4,Thomale Ulrich‐Wilhelm5,Pennacchietti Valentina5,Tietze Anna4,Horn Denise6,Pajtler Kristian W.789,Hirsch Steffen8910,Wieland Ilse11,Deubzer Hedwig1213,Rossi Rainer14,Driever Pablo Hernáiz12,von Hoff Katja12,von Zezschwitz Barbara12

Affiliation:

1. Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt‐Universität zu Berlin, Department of Neuropathology Berlin Germany

2. German Cancer Consortium (DKTK), Partner Site Berlin, German Cancer Research Center (DKFZ) Heidelberg Germany

3. Division of Translational Pathology, Gerhard Domagk Institute of Pathology University Hospital Münster Münster Germany

4. Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt‐Universität zu Berlin, Department of Neuroradiology Berlin Germany

5. Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt‐Universität zu Berlin, Department of Neurosurgery, Division Pediatric Neurosurgery Berlin Germany

6. Institute of Medical and Human Genetics, Charité ‐ Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt‐Universität zu Berlin, and Berlin Institute of Health Berlin Germany

7. Department of Pediatric Oncology, Hematology and Immunology Heidelberg University Hospital Heidelberg Germany

8. Division of Pediatric Neurooncology, German Cancer Consortium German Cancer Research Center (DKFZ) Heidelberg Germany

9. Hopp Children's Cancer Center Heidelberg (KiTZ) Heidelberg Germany

10. Institute of Human Genetics University Hospital Heidelberg Heidelberg Germany

11. Institute of Human Genetics University Hospital Magdeburg Magdeburg Germany

12. Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt‐Universität zu Berlin, Department of Pediatric Oncology and Hematology Berlin Germany

13. Experimental and Clinical Research Center (ECRC) of the Charité and the Max‐Delbrück‐Center for Molecular Medicine (MDC) in the Helmholtz Association Berlin Germany

14. Department of Paediatrics, Vivantes Neukölln Hospital, Vivantes Hospital Group, Charité Academic Teaching Hospital Berlin Germany

Publisher

Wiley

Subject

Physiology (medical),Neurology (clinical),Neurology,Histology,Pathology and Forensic Medicine

Reference14 articles.

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