Vaccine‐induced immune thrombotic thrombocytopenia (VITT) – a novel clinico‐pathological entity with heterogeneous clinical presentations

Author:

Lavin Michelle12ORCID,Elder Patrick T.3,O’Keeffe Denis4,Enright Helen5,Ryan Eileen5,Kelly Anna6,El Hassadi Ezzat7,McNicholl Feargal P.3,Benson Gary8,Le Giao N.1,Byrne Mary1,Ryan Kevin1,O’Connell Niamh M.1,O’Donnell James S.12

Affiliation:

1. National Coagulation Centre St. James’s Hospital DublinIreland

2. Irish Centre for Vascular Biology School of Pharmacy and Biomedical Sciences RCSI Dublin Ireland

3. North West Cancer Centre Altnagelvin Area Hospital Derry Northern Ireland

4. Department of Haematology University Hospital Limerick LimerickIreland

5. Department of Haematology Tallaght University Hospital DublinIreland

6. Department of Medicine Wexford General Hospital WexfordIreland

7. Department of Haematology University Hospital Waterford Waterford Ireland

8. Haemophilia and Thrombosis Centre Belfast City Hospital Belfast Northern Ireland UK

Funder

3M Foundation

Health Research Board

Publisher

Wiley

Subject

Hematology

Reference12 articles.

1. EMA & AstraZeneca.VAXZEVRIA/COVID‐19 Vaccine AstraZeneca : link between the vaccine and the occurrence of thrombosis in combination with thrombocytopenia[cited 2021 April 21]. Available at:https://www.ema.europa.eu/en/documents/dhpc/direct‐healthcare‐professional‐communication‐dhpc‐vaxzevria‐previously‐covid‐19‐vaccine‐astrazeneca_en‐0.pdf.

2. Centers for Disease Control and Prevention.Joint CDC and FDA Statement on Johnson & Johnson COVID‐19 Vaccine[cited 2021 April 21]. Available at:https://www.cdc.gov/media/releases/2021/s0413‐JJ‐vaccine.html.

3. Thrombosis and Thrombocytopenia after ChAdOx1 nCoV-19 Vaccination

4. Thrombotic Thrombocytopenia after ChAdOx1 nCov-19 Vaccination

5. Pathologic Antibodies to Platelet Factor 4 after ChAdOx1 nCoV-19 Vaccination

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