Hepatitis B virus surface protein mutations clustered mainly in CTL immune epitopes in chronic carriers: results of an Iranian nationwide study

Author:

Khedive A.1,Norouzi M.1,Ramezani F.1,Karimzadeh H.1,Alavian S. M.2,Malekzadeh R.3,Montazeri G.3,Nejatizadeh A.4,Ziaee M.5,Abedi F.6,Ataei B.7,Yaran M.7,Sayad B.8,Somi M. H.9,Sarizadeh G.10,Sanei-Moghaddam I.11,Mansour-Ghanaei F.12,Rafatpanah H.13,Pourhosseingholi M. A.14,Keyvani H.15,Kalantari E.16,Saberifiroozi M.17,Judaki M. A.1,Ghamari S.1,Daram M.1,Mahabadi M.1,Fazeli Z.1,Goodarzi Z.1,Poortahmasebi V.1,Jazayeri S. M.1

Affiliation:

1. Hepatitis B Molecular Laboratory; Department of Virology; School of Public Health; Tehran University of Medical Sciences; Tehran Iran

2. Middle East Liver Diseases Center (MELD Centers); Tehran Iran

3. Digestive Disease Research Center; Tehran University of Medical Sciences; Tehran Iran

4. Research Center for Molecular Medicine; Hormozgan University of Medical Sciences; Bandar Abbas Iran

5. Department of Internal Medicine; Vali-e-Asr Hospital; Birjand University of Medical Sciences; Birjand Iran

6. Department of Infectious Disease; Mashhad University of Medical Sciences; Mashhad Iran

7. Infectious Diseases and Tropical Medicine Research Center; Isfahan University of Medical Sciences; Isfahan Iran

8. Kermanshah Liver Diseases and Hepatitis Research Center; Kermanshah Iran

9. Liver and Gastrointestinal Disease Research Center; Tabriz University of Medical Sciences; Tabriz Iran

10. Educational Region of Khozestan Blood Transfusion Organization; Ahvaz Iran

11. Department of Gastroenterology; Zahedan University of Medical Sciences; Zahedan Iran

12. Gastrointestinal & Liver Diseases Research Center; Guilan University of Medical Sciences; Rasht Iran

13. Immunology Research Center; Mashhad University of Medical Sciences; Mashhad Iran

14. Gastroenterology and Liver Diseases Research Center; Shahid Beheshti University of Medical Sciences; Tehran Iran

15. Department of Virology, School of Medicine; Tehran University of Medical Sciences; Tehran Iran

16. Gholhack Medical Laboratory; Tehran Iran

17. Digestive Disease Research Center and Gastroenterohepatology Research Center; Tehran and Shiraz University of Medical Sciences; Tehran and Shiraz Iran

Funder

Tehran University of Medical Sciences

Publisher

Wiley

Subject

Virology,Infectious Diseases,Hepatology

Reference48 articles.

1. Treatment of hepatitis B virus cirrhosis;Rizzetto;Hepat Mon,2012

2. Efficacy of Hepatitis B vaccine in those who lost Hepatitis B surface antigen during follow-up: efficacy of HBV vaccine in those who lost HBsAg;Taheri;Hepat Mon,2011

3. The cytotoxic T lymphocyte response to multiple hepatitis B virus polymerase epitopes during and after acute viral hepatitis;Rehermann;J Exp Med,1995

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