Risk and Reward: Nationwide Analysis of Cardiac Transplant Center Variation in Organ Travel Distance and the Effects on Outcomes

Author:

Seadler Benjamin D.1ORCID,Karra Hamsitha1,Zelten James1,Rein Lisa E.2,Durham Lucian A.1,Joyce Lyle D.1,Kohmoto Takushi1,Joyce David L.3

Affiliation:

1. Division of Cardiothoracic Surgery Medical College of Wisconsin Milwaukee Wisconsin USA

2. Institute for Health & Equity Division of Biostatistics Medical College of Wisconsin Milwaukee Wisconsin USA

3. Cardiothoracic Surgery Eastern Idaho Regional Medical Center Idaho Falls Idaho USA

Abstract

ABSTRACTBackgroundThe 2018 UNOS allocation policy change deprioritized geographic boundaries to organ distribution, and the effects of this change have been widespread. The aim of this investigation was to analyze changes in donor transplant center distance for organ travel and corresponding outcomes before and after the allocation policy change.MethodsThe UNOS database was utilized to identify all adult patients waitlisted for heart transplants from 2016 to 2021. Transplant centers were grouped by average donor heart travel distance based on whether they received more or less than 50% of organs from >250 miles away. Descriptive statistics were provided for waitlisted and transplanted patients. Regression analyses modeled waitlist mortality, incidence of transplant, overall survival, and graft survival.ResultsCenters with a longer average travel distance had a higher mean annual transplant volume with a reduction in total days on a waitlist (86.6 vs. 149.2 days), an increased cold ischemic time (3.6 vs. 3.2 h), with no significant difference in post‐transplant overall survival or graft survival.ConclusionsThe benefits of reducing waitlist time while preserving post‐transplant outcomes extend broadly. The trends observed in this investigation will be useful as we revise organ transplant policy in the era of new organ procurement and preservation techniques.

Publisher

Wiley

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