Protective effect of soluble Klotho in pediatric patients undergoing cardiac surgery with cardiopulmonary bypass support

Protective effect of soluble Klotho in pediatric patients undergoing cardiac surgery with cardiopulmonary bypass support—A pilot study

Published:2021-08-05 Issue:10 Volume:36 Page:3567-3576
ISSN:0886-0440
Container-title:Journal of Cardiac Surgery
language:en
Short-container-title:J Card Surg

Author:

Pode Shakked Naomi¹²³,Rosenblat Orgad¹⁴,Sagiv Doron¹³⁵,Molad Jeremy¹⁶,Weinberg Hagai¹⁷,Shlomo Meital¹²,Tokatly Latzer Itay¹²,Pleniceanu Oren¹⁸,Mishali David¹⁹,Vardi Amir¹¹⁰,Hemi Rina¹¹¹,Kanety Hannah¹¹¹,Paret Gideon¹²

Affiliation:

1. Sackler Faculty of Medicine Tel‐Aviv University Tel‐Aviv Israel

2. Department of Pediatric Intensive Care, Edmond and Lily Safra Children's Hospital Sheba Medical Center Tel‐Hashomer Israel

3. The Talpiot Medical Leadership Program Sheba Medical Center Tel‐Hashomer Israel

4. Department of Obstetrics and Gynecology Sheba Medical Center Ramat Gan Israel

5. Department of Otolaryngology Head and Neck Surgery Sheba Medical Center Tel‐Hashomer Israel

6. Department of Neurology Tel Aviv Sourasky Medical Center Tel Aviv Israel

7. Internal Medicine B Meir Medical Center Kfar Saba Israel

8. Kidney Research Lab, The Institute of Nephrology and Hypertension Sheba Medical Center Tel‐Hashomer Israel

9. Pediatric and Congenital Cardiac Surgery, Edmond and Safra International Congenital Heart Center, The Edmond and Lily Safra Children's Hospital Sheba Medical Center Tel Hashomer Israel

10. Pediatric Cardiac Intensive Care Unit, Edmond and Safra International Congenital Heart Center, The Edmond and Lily Safra Children's Hospital Sheba Medical Center Tel Hashomer Israel

11. Institute of Endocrinology Sheba Medical Center Tel‐Hashomer Israel

Publisher

Wiley

Subject

Cardiology and Cardiovascular Medicine,Surgery,Pulmonary and Respiratory Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/jocs.15849

Reference37 articles.

1. Renal Klotho is Reduced in Septic Patients and Pretreatment With Recombinant Klotho Attenuates Organ Injury in Lipopolysaccharide-Challenged Mice

2. Reduced Klotho is associated with the presence and severity of coronary artery disease

3. Acute Renal Insufficiency and Renal Replacement Therapy After Pediatric Cardiopulmonary Bypass Surgery

4. Oxidative stress precedes peak systemic inflammatory response in pediatric patients undergoing cardiopulmonary bypass operation

5. PEDIATRIC CARDIAC SURGERY WITH CARDIOPULMONARY BYPASS: PATHWAYS CONTRIBUTING TO TRANSIENT SYSTEMIC IMMUNE SUPPRESSION

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1. The Klotho protein and FGF23 as well-known players in the aging process but underestimated in the process of individual development and selected diseases of childhood and adolescence – a systematic review;Pediatria i Medycyna Rodzinna;2024-07-11

2. Klotho as an Early Marker of Acute Kidney Injury Following Cardiac Surgery: A Systematic Review;Journal of Cardiovascular Development and Disease;2024-04-28

3. Aging-suppressor Klotho: Prospects in diagnostics and therapeutics;Ageing Research Reviews;2022-12

4. Protective effect of soluble Klotho in pediatric patients undergoing cardiac surgery with cardiopulmonary bypass support‐what do we need to consider?;Journal of Cardiac Surgery;2021-09-07