Prazosin + Naltrexone Decreases Alcohol Drinking More Effectively Than Does Either Drug Alone in P Rats with a Protracted History of Extensive Voluntary Alcohol Drinking, Dependence, and Multiple Withdrawals

Author:

Rasmussen Dennis D.123,Kincaid Carrie L.23,Froehlich Janice C.4

Affiliation:

1. VISN 20 Mental Illness Research, Education and Clinical Center; Seattle Washington

2. VA Puget Sound Health Care System; Seattle Washington

3. Department of Psychiatry and Behavioral Sciences; University of Washington; Seattle Washington

4. Department of Medicine; Indiana University School of Medicine; Indianapolis Indiana

Funder

VA Puget Sound Health Care System

VA VISN 20 Mental Illness Research, Education and Clinical Center (MIRECC)

NIH

Publisher

Wiley

Subject

Psychiatry and Mental health,Toxicology,Medicine (miscellaneous)

Reference53 articles.

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2. Combined pharmacotherapies and behavioral interventions for alcohol dependence. The COMBINE study: a randomized controlled trial;Anton;JAMA,2006

3. The alcohol-preferring P rat and animal models of excessive alcohol drinking;Bell;Addict Biol,2006

4. The dopamine β-hydroxylase inhibitory, nepicastat, reduces different alcohol-related behaviors in rats;Colombo;Alcohol Clin Exp Res,2014

5. Activation of the locus coeruleus noradrenergic system by intracoerulear microinfusion of corticotropin-releasing factor: effects on discharge rate, cortical norepinephrine levels and cortical electroencephalographic activity;Curtis;J Pharmacol Exp Ther,1997

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