NS383 Selectively Inhibits Acid-Sensing Ion Channels Containing 1a and 3 Subunits to Reverse Inflammatory and Neuropathic Hyperalgesia in Rats
Author:
Affiliation:
1. NeuroSearch A/S; Ballerup Denmark
2. Saniona A/S; Ballerup Denmark
3. Faculty of Pharmacy; The University of Sydney; Sydney NSW Australia
Funder
IMK Almene Fond, Denmark
Publisher
Wiley
Subject
Pharmacology (medical),Physiology (medical),Psychiatry and Mental health,Pharmacology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/cns.12487/fullpdf
Reference51 articles.
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2. Acid-sensing ion channels (ASICs): Pharmacology and implication in pain;Deval;Pharmacol Ther,2010
3. Structure of acid-sensing ion channel 1 at 1.9 A resolution and low pH;Jasti;Nature,2007
4. Pharmacology of acid-sensing ion channels -Physiological and therapeutical perspectives;Baron;Neuropharmacology,2015
5. pH Dependency and desensitization kinetics of heterologously expressed combinations of acid-sensing ion channel subunits;Hesselager;J Biol Chem,2004
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