Delivery of an anti-transthyretin Nanobody to the brain through intranasal administration reveals transthyretin expression and secretion by motor neurons
Author:
Affiliation:
1. Instituto de Investigação e Inovação em Saúde (I3S); University of Porto; Porto Portugal
2. Neurobiology Unit; IBMC- Institute for Molecular and Cell Biology; University of Porto; Porto Portugal
3. ABLYNX; Ghent Belgium
Funder
Federación Española de Enfermedades Raras
Fundação para a Ciência e a Tecnologia
QREN Brainiac
post-doctoral fellowship
Publisher
Wiley
Subject
Cellular and Molecular Neuroscience,Biochemistry
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/jnc.14332/fullpdf
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3. The diversity of mechanisms influenced by transthyretin in neurobiology: development, disease and endocrine disruption;Alshehri;J. Neuroendocrinol.,2015
4. Early involvement of motor nerve dysfunction in atypical cases with familial amyloidotic polyneuropathy (FAP) type I;Ando;Muscle Nerve,1993
5. A peculiar form of peripheral neuropathy; familiar atypical generalized amyloidosis with special involvement of the peripheral nerves;Andrade;Brain,1952
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