Atipamezole, a specific α 2A antagonist, suppresses spike‐and‐wave discharges and alters Ca 2⁺ /calmodulin‐dependent protein kinase II in the thalamus of genetic absence epilepsy rats-Reference-Cited by-同舟云学术

Atipamezole, a specific α 2A antagonist, suppresses spike‐and‐wave discharges and alters Ca 2⁺ /calmodulin‐dependent protein kinase II in the thalamus of genetic absence epilepsy rats

Published:2020-10-23 Issue:12 Volume:61 Page:2825-2835
ISSN:0013-9580
Container-title:Epilepsia
language:en
Short-container-title:Epilepsia

Author:

Yavuz Melis¹²^ORCID,Aydın Banu³^ORCID,Çarçak Nihan⁴^ORCID,Akman Özlem⁵^ORCID,Raci Yananlı Hasan²^ORCID,Onat Filiz²⁶⁷^ORCID

Affiliation:

1. Department of Pharmacology Faculty of Pharmacy Acibadem Mehmet Ali Aydinlar University Istanbul Turkey

2. Department of Medical Pharmacology Faculty of Medicine Marmara University Istanbul Turkey

3. Department of Biophysics Faculty of Medicine Marmara University Istanbul Turkey

4. Department of Pharmacology Faculty of Pharmacy Istanbul University Istanbul Turkey

5. Department of Physiology Faculty of Medicine Demiroglu Bilim University Istanbul Turkey

6. Epilepsy Research Center Marmara University Istanbul Turkey

7. Department of Medical Pharmacology Faculty of Medicine Acibadem Mehmet Ali Aydinlar University Istanbul Turkey

Funder

Marmara Üniversitesi

Publisher

Wiley

Subject

Neurology (clinical),Neurology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/epi.16728

Reference43 articles.

1. Lack of the Burst Firing of Thalamocortical Relay Neurons and Resistance to Absence Seizures in Mice Lacking α1G T-Type Ca2+ Channels

2. Suppression of Hyperpolarization-Activated Cyclic Nucleotide-Gated Channel Function in Thalamocortical Neurons Prevents Genetically Determined and Pharmacologically Induced Absence Seizures

3. α2A Adrenergic Receptor Activation Inhibits Epileptiform Activity in the Rat Hippocampal CA3 Region

4. The anticonvulsant and proconvulsant effects of α2-adrenoreceptor agonists are mediated by distinct populations of α2a-adrenoreceptors

5. Reduction of adrenergic neurotransmission with clonidine aggravates spike-wave seizures and alters activity in the cortex and the thalamus in WAG/Rij rats

Cited by 12 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Adrenergic receptor system as a pharmacological target in the treatment of epilepsy (Review);Medicine International;2024-02-27

2. Alpha‐2a adrenergic receptor activation in genetic absence epilepsy: An absence status model?;Epilepsia Open;2024-01-18

3. Dexmedetomidine, an alpha 2A receptor agonist, triggers seizures unilaterally in GAERS during the pre-epileptic phase: does the onset of spike-and-wave discharges occur in a focal manner?;Frontiers in Neurology;2023-12-11

4. Involvement of orexin type-2 receptors in genetic absence epilepsy rats;Frontiers in Neurology;2023-11-30

5. Adrenergic mechanisms of absence status epilepticus;Frontiers in Neurology;2023-11-22