Influence of CYP2C19 loss-of-function variants on the metabolism of clopidogrel in patients from north-western China
Author:
Affiliation:
1. School of Pharmacology; Health Science Center; Xi'an Jiaotong University; Xi'an China
2. School of Pharmacy; Health Science Center; Xi'an Jiaotong University; Xi'an China
3. Health Science Center; Xi'an Jiaotong University; Xi'an China
Funder
First Affiliated Hospital of Xi'an Jiaotong University
National Natural Science Foundation of China grant
Publisher
Wiley
Subject
Pharmacology (medical),Pharmacology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/jcpt.12254/fullpdf
Reference32 articles.
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3. The Effect of CYP2C19 Genotype on the Time Course of platelet aggregation inhibition after clopidogrel administration;Kim;J Clin Pharmacol,2014
4. Identification of the human cytochrome P450 enzymes involved in the two oxidative steps in the bioactivation of clopidogrel to its pharmacologically active metabolite;Kazui;Drug Metab Dispos,2010
5. Determinants to optimize response to clopidogrel in acute coronary syndrome;Giusti;Pharmgenomics Pers Med,2010
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