Reversal of visceral hypersensitivity in rat by Menthacarin®, a proprietary combination of essential oils from peppermint and caraway, coincides with mycobiome modulation

Author:

Botschuijver S.1,Welting O.1,Levin E.23,Maria-Ferreira D.145,Koch E.6,Montijn R. C.7,Seppen J.1,Hakvoort T. B. M.1,Schuren F. H. J.7,de Jonge W. J.1,van den Wijngaard R. M.1ORCID

Affiliation:

1. Department of Gastroenterology and Hepatology, Academic Medical Center; Tytgat Institute for Liver and Intestinal Research; Amsterdam The Netherlands

2. Department of Experimental Vascular Medicine; Academic Medical Center; Amsterdam The Netherlands

3. Horaizon BV; Rotterdam The Netherlands

4. Departamento de Farmacologia, Setor de Ciências Biológicas; Universidade Federal do Paraná; Curitiba PR Brazil

5. Departamento de Bioquímica e Biologia Molecular; Universidade Federal do Paraná; Curitiba PR Brazil

6. Dr. Willmar Schwabe Pharmaceuticals; Karlsruhe Germany

7. Microbiology and Systems Biology; The Netherlands Organization for Applied Scientific Research (TNO); Zeist The Netherlands

Funder

The Netherlands Digestive Diseases Foundation

Dr. Willmar Schwabe Pharmaceuticals, Karlsruhe, Germany

Publisher

Wiley

Subject

Gastroenterology,Endocrine and Autonomic Systems,Physiology

Reference48 articles.

1. Bowel disorders;Mearin;Gastroenterology,2016

2. Irritable bowel syndrome: methods, mechanisms, and pathophysiology. Methods to assess visceral hypersensitivity in irritable bowel syndrome;Keszthelyi;Am J Physiol Gastrointest Liver Physiol,2012

3. Intestinal fungal dysbiosis associates with visceral hypersensitivity in patients with irritable bowel syndrome and rats;Botschuijver;Gastroenterology,2017

4. In vitro antifungal activity of terpinen-4-ol, eugenol, carvone, 1,8-cineole (eucalyptol) and thymol against mycotoxigenic plant pathogens;Morcia;Food Addit Contam Part A Chem Anal Control Expo Risk Assess,2012

5. Chemical composition of essential oils of Thymus and Mentha species and their antifungal activities;Sokovic;Molecules,2009

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