Benefit and potential risk: Effects of in ovo copper oxide nanoparticles supplementation on hatchability traits, organ weights and histological features of newly hatched chicks

Author:

Issa Hussien Jamil1,Hassan Mohamed I.2ORCID,Mekkawy Aya M.3ORCID,El Sabry Mohamed I.4ORCID,Abousekken Mahmoud Saad M.1ORCID

Affiliation:

1. Department of Sustainability Development, Environmental Studies and Research Institute University of Sadat City Sadat City Egypt

2. Livestock Research Department Arid Lands Cultivation Research Institute, City of Scientific Research and Technological Applications (SRTA‐ City), New Borg El‐Arab Alexandria Egypt

3. Department of Cytology and Histology, Faculty of Veterinary Medicine Cairo University Giza Egypt

4. Department of Animal Production, Faculty of Agriculture Cairo University Giza Egypt

Abstract

AbstractThis investigation was directed to examine the influence of copper oxide nanoparticles (CuO‐NPs) on the hatchability traits, and chick quality of newly hatched broiler chicks. A total of 480 eggs were randomly divided into four treatment groups, each consisting of three duplicates. As a negative control (NC), the first group was not injected; the second group was injected with saline and served as a positive control (PC), the third and fourth groups were injected with 30 and 60 ppm of (CuO‐NPs)/egg. Eggs were injected into the amniotic fluid on the eighteenth day of the incubation period. Results showed that the hatchability, chick yield %, yolk free‐body mass (YFBM), chick length, shank length (SL), and relative weight of the heart, gizzard and intestine of day‐old broiler chicks were all unaffected by the in ovo injection of CuO‐NPs. The Pasgar Score was slightly improved compared to the NC and PC groups. Also, the in ovo administration of CuO‐NPs (60 ppm/egg) significantly increased the intestine length. Both levels of CuO‐NPs significantly increased the concentration of Cu ions in the hepatic tissue. Additionally, different levels of tissue damage were seen in the liver of the birds that were given low or high dosages of CuO‐NPs. Conclusively, the in ovo injection of CuO‐NPs has a good result on the appearance of the chicks (Pasgar score). However, negative effect of CuO‐NPs on liver tissue may raise concerns about the potential risks of applying CuO‐NPs in ovo administration.

Publisher

Wiley

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