Clinical and economic burden of benign and malignant skin lesions in renal transplant recipients

Author:

Thet Zaw12ORCID,Lam Alfred K.13ORCID,Pham Tony2,Ng Shu‐Kay13,Steel Jason C.4,Sawhney Sirena2,Arellano Carolina T.5,Aung Soe Yu56,Han Thin25,Ranganathan Dwarakanathan17,John George7,Pepito Christina2,Rautenberg Tamlyn389,Khoo Tien K.1310

Affiliation:

1. School of Medicine and Dentistry Griffith University Brisbane Queensland Australia

2. Department of Nephrology Central Queensland Hospital and Health Service Rockhampton Queensland Australia

3. Menzies Health Institute Queensland Gold Coast Queensland Australia

4. School of Health, Medical and Applied Sciences Central Queensland University Rockhampton Queensland Australia

5. Rural Clinical School University of Queensland Rockhampton Queensland Australia

6. Department of Medical Oncology Central Queensland Hospital and Health Service Rockhampton Queensland Australia

7. Department of Nephrology Metro North Hospital and Health Service Brisbane Queensland Australia

8. Centre for Applied Health Economics, School of Medicine and Dentistry Griffith University Brisbane Queensland Australia

9. Allied health Metro North Hospital and Health Service Brisbane Queensland Australia

10. School of Medicine University of Wollongong Wollongong New South Wales Australia

Abstract

AbstractBackgroundStudies evaluating the economic burden of dermatological care in the transplant setting are currently not available in Australia.AimsTo evaluate the clinical and economic burden of benign and malignant skin lesions in renal transplant recipients in Central Queensland.MethodsA bottom‐up approach was used to determine the clinical burden and direct costs from patient‐level Medicare data obtained from Service Australia for skin lesions.ResultsSeventy‐six percent of the renal transplant population in Central Queensland participated in this study. The median age was 57.0 years (standard deviation ± 13.6) and the majority (61.8%) of participants were men. The mean duration after transplant surgery was 99.9 months (interquartile range, 73.2–126.6 months). During a 2‐year follow‐up, 22 (40%) patients were diagnosed with benign skin lesions, 21 (38%) with nonmelanoma skin carcinoma (NMSC) and one (2%) with melanoma. There was a total of 231 visits to clinicians for diagnostic and therapeutic skin procedures and the direct costs to Medicare was $48 806 Australian Dollars (AUD) or $30 427 US Dollars (USD). Approximately 86% of the total direct costs was spent for nonNMSC and mean direct costs for NMSC was $763 AUD (or $476 USD).ConclusionThis Medicare data‐based study provides further insight into the burgeoning clinical and economic burden of the care for benign and malignant skin lesions in the renal transplantation setting in Australia.

Publisher

Wiley

Subject

Internal Medicine

Reference31 articles.

1. 2021 Australian Donation and Transplantation – Statistics in Australia: Activity Report. Available from URL:http://www.donatelife.gov.au

2. Australia & New Zealand Dialysis and Transplant Registry. ANZDATA 44th Annual Report 2021. Available from URL:http://www.anzdata.org.au

3. Skin cancer in organ transplant recipients: More than the immune system

4. Skin Cancers in Organ Transplant Recipients

5. Skin cancer in organ transplant recipients: dynamics in the incidence and clinical predictors for the first and subsequent post‐transplant non‐melanoma skin cancer

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