A potential therapeutic effect of saikosaponin C as a novel dual-target anti-Alzheimer agent-Reference-Cited by-同舟云学术

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A potential therapeutic effect of saikosaponin C as a novel dual-target anti-Alzheimer agent

Published:2016-01-21 Issue:6 Volume:136 Page:1232-1245
ISSN:0022-3042
Container-title:Journal of Neurochemistry
language:en
Short-container-title:J. Neurochem.

Author:

Lee Tae Ho¹,Park Sungha²,You Mi-Hyeon¹,Lim Ji-Hong³,Min Sang-Hyun⁴,Kim Byeong Mo²

Affiliation:

1. Division of Gerontology; Department of Medicine; Beth Israel Deaconess Medical Center; Harvard Medical School; Boston Massachusetts USA

2. Severance Integrative Research Institute for Cerebral & Cardiovascular Diseases (SIRIC); Yonsei University College of Medicine; Seoul Korea

3. Department of Biomedical Chemistry; College of Biomedical and Health Science; Konkuk University; Chungju Korea

4. New Drug Development Center; DGMIF; Daegu Korea

Funder

Korea Healthcare technology R&D Project, Ministry for Health & Welfare Affairs

National Research Foundation of Korea

Ministry of Science, ICT and Future Planning

Publisher

Wiley

Subject

Cellular and Molecular Neuroscience,Biochemistry

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/jnc.13515/fullpdf

Reference59 articles.

1. Cerebrospinal fluid beta-amyloid((1-42)) in Alzheimer disease - Differences between early- and late-onset Alzheimer disease and stability during the course of disease;Andreasen;Arch. Neurol.,1999

2. Classic beta-amyloid deposits cluster around large diameter blood vessels rather than capillaries in sporadic Alzheimer's disease;Armstrong;Curr. Neurovasc. Res.,2006

3. Amyloid beta-peptide induces cell monolayer albumin permeability, impairs glucose transport, and induces apoptosis in vascular endothelial cells;Blanc;J. Neurochem.,1997

4. Abnormal tau-phosphorylation at Ser(396) in Alzheimers-disease recapitulates development and contributes to reduced microtubule-binding;Bramblett;Neuron,1993

5. Differential diagnosis of Alzheimer disease with cerebrospinal fluid levels of tau protein phosphorylated at threonine 231;Buerger;Arch. Neurol.,2002

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