Population pharmacokinetics of doxorubicin and doxorubicinol in patients diagnosed with non-Hodgkin's lymphoma

Author:

Pérez-Blanco Jonás Samuel12,Santos-Buelga Dolores12,Fernández de Gatta María del Mar12,Hernández-Rivas Jesús María23,Martín Alejandro23,García María José12

Affiliation:

1. Department of Pharmaceutical Sciences - Pharmacy and Pharmaceutical Technology; University of Salamanca; Spain

2. Salamanca Institute for Biomedical Research (IBSAL); Salamanca Spain

3. Haematology Department; University Hospital of Salamanca and IBMCC, Cancer Research Centre; Salamanca Spain

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Reference54 articles.

1. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands;Southan;Nucl. Acids Res,2016

2. Anthracyclines in the treatment of cancer;Hortobágyi;An overview. Drugs,1997

3. Doxorubicin cardiotoxicity may be caused by its metabolite, doxorubicinol;Olson;Proc Natl Acad Sci U S A,1988

4. Concentrations of doxorubicin and its metabolites in human autopsy heart and other tissues;Stewart;Anticancer Res,1993

5. Time-related increases in cardiac concentrations of doxorubicinol could interact with doxorubicin to depress myocardial contractile function;Mushlin;Br J Pharmacol,1993

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